The Hype About Hair Cloning

written by: Kelly Makay; article published: year 2010, month 06;

In: Root » Health » Hair loss

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Modern hair transplants can greatly improve your appearance, but they have limitations. You can only transplant as much hair as is available in donor areas, and the older you get, the balder you get, so you need to cover larger bald areas with decreasing amounts of donor hair.

But what if you could clone your hair have one hair replicated in the lab so that it would produce many hairs? The donor supply would be limitless. As simple as hair looks to the naked eye, it may seem that cloning hair wouldn’t be all that difficult. There’s a lot more to hair, however, than meets the eye. Hair follicles are complex, containing skin cells, fat, blood vessels, nerves, muscles, and glands.

There’s also a lot more to hair cloning; potential methods include genetic engineering of the cells, so you never lose your hair in the first place, as well as developing techniques to multiply your own hair cells; we discuss them all in the next sections. “Inducing” new hair growth

In the late 1990s, a British scientist named Dr. Jahoda took dermal sheath cells (cells from the lowest part of the hair follicle) from his own scalp and transplanted them into his wife’s forearm. These cells stimulated new hair growth on his wife’s arm, and the cells, when analyzed, contained both of the couple’s DNA. The fact that his DNA was in her forearm conclusively showed that, at least in this one surgery, he had conquered part of the cloning process. The results of this experiment have two interesting applications for future hair cloning:

  • The dermal sheath cells act as “inducer” cells, inducing new hair growth without having to transplant the whole hair follicle.
  • The dermal sheath cells seem to be immune privileged organs, which means they can be transplanted from one person to another without being rejected.

Even more importantly from a cloning perspective is that “inducer” dermal sheath cells are fibroblasts, which are among the easiest cells to culture. If these cells can be cultured in the lab, a person’s own donor area could potentially serve as an unlimited source of hair for the cloning process. That’s what everyone wants to hear, but at the time of writing this article, the cloning process clearly isn’t there yet. Look for more advances in this area, though! Some issues and problems to overcome in the area of hair cloning include:

  • Dermal sheath cells are difficult to isolate.
  • The ability to culture the cells has to be proven.
  • The cells need to grow in the right direction through the scalp instead of under the skin or downward.
  • It’s not certain that the induced follicles will continue to grow hair after the initial hair growth is shed (normal hair grows in cycles of two to six years).
  • The cultured cells may revert to an undifferentiated state and stop growing hair over time.
  • It’s unknown whether the inducer cells may also induce tumors or encourage malignant growths.
  • FDA testing and approval will take years.

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